Budweiser’s Internal Constraints

Budweiser is produced by Anheuser-Busch Companies (Anheuser-Busch), one of the world's largest brewers best known for its Budweiser and Bud Light brands. The group is a leading brewer and operates 12 breweries in the United States (Company Website, 2007). As a company, Anheuser-Busch’s internal constraints are as follows: 1. High dependence on domestic beer division Although the company operates through four business segments including domestic beer, international beer, packaging and entertainment it is still dependant on the domestic beer segment for majority of its revenue.During the fiscal year ending 2006, company generated approximately 74. 8% of its total revenue from the domestic beer segment. In contrast the other three segments accounted for only 25. 2 % of the total revenue during the same period. Strong dependence on a particular segment increases the business risk of the company thereby putting it in a competitive disadvantage (Anheuser-Busch Annual Report, 2006). This is why Anheuser-Busch is currently battling for a presence in China, the world’s largest beer market, as state owned breweries seek foreign help with privatization.In 2004, Anheuser-Busch outbid Miller for the Harbin Brewing Group of China (Modern Brewery Age, Weekly News Edition, June 14, 2004). This year, Anheuser-Busch may acquire Scottish & Newcastle's 37. 5% stake in India-based United Breweries. 2. ) Poor liquidity position Anheuser-Busch has substantial outstanding long-term debt. As of December 2006, the company had long term debt of approximately $7,653. 5 million. The company's debt equity ratio is 2. 2 times which is quite high as compared to industry average of 1. 3 times.The company's interest coverage ratio is 6. 2 as compared to industry average of 10. 1 times (Anheuser-Busch Annual Report, 2006). This ratio clearly signifies that the liquidity position of the company is bad and this would hamper company’s credibility in the market and would be diff icult for them to raise money from the market for their expansion plans. 3. ) High dependence on wholesalers Anheuser-Busch sells substantially all of its beer to independent wholesalers for distribution to retailers and ultimately consumers.During 2006, approximately 94% of the beer sold by the company, reached retail channels through more than 600 independent wholesalers (Anheuser-Busch Annual Report, 2006). In 2007, Anheuser-Busch was appointed as the United States importer for a number of the premium European brands of InBev (International Herald Tribune, 4 February 2008). Many of the wholesalers of these brands have not traditionally been wholesalers for Anheuser-Busch. As independent companies, wholesalers make their own business decisions that may not always align themselves with the company's interests.Dependence of the company on the wholesalers may affect the bargaining power of the company in the market, thus affecting its financial performance. Works Cited Anheuser-Busch . About the Company. Anheuser-Busch Website. 7 Feb. 2007. http://www. anheuser-busch. com/Company. html. Anheuser-Busch. Anheuser-Busch Annual Report, 2006. 7 Feb. 2007. http://www. anheuser-busch. com/Stock/2006AR_Anheuser_Busch. pdf. International Herald Tribune. InBev Linked with Mergers, 4 February 2008. Modern Brewery Age, Weekly News Edition. Anheuser is Victor in Harbin Bidding War, 14 June 2004.

Media Studies

April 5, 2013Unit 3 – Lesson 14 – Key Question #30Keitlin Okell In today’s society the media can portray different â€Å"groups† in certain ways towards society. One of these groups are teenagers; the realities that are portrayed within this specific group can be very misunderstood or very accurate depending on what is â€Å"seen† and â€Å"not seen†, values are also constructed within the media around us as teenagers not valuing what was valued in the past generations.Finally with the different media surrounding everyone’s lives, the commercial factors do influence the media with the â€Å"teenager† topic with giving teenagers a bad image sometimes but however the commercial factors can give a positive look on teenagers. If people were asked what their first thoughts of when they heard the word â€Å"teenager†, the first thoughts that come to their mind will probably shock you, with it being; negative, wild, irresponsibl e, immortal, violent, monsters, etc. These type of thoughts that are constructed about teenagers come from the media and what is â€Å"seen† and â€Å"not seen†.What is seen in the media the â€Å"glamorous† lifestyles of teenagers that go out to drink, party, abuse alcohol and drugs, deal with violence, and other inappropriate actions; all these actions are shown within movies, TV shows (reality or not), newspaper and even music. An example is the movie â€Å"Mean Girls†, this movie is about cliches, and how the high school life â€Å"is†, with the lies, sex, drinking, and not showing the positives of being a teenager and the difficulties that every teenager goes through. The media doesn’t show the hard part of being a teenager such as being bullied, exams, stress and insecurities.Also what is not shown within the media about teenagers is that they do care about politics, society’s issues, the environment, volunteering, their school work and other positive activities. Realistic wise, the media over exaggerates the topic of being a teenager because the media thrives on scandals even if that includes over reacting the â€Å"life of a teenager†; this is to get the audiences reaction, awareness and entertainment all at once. The values that are represented about teenagers are right but are also wrong.The negative values that are represented for teenagers is that they don’t care about â€Å"anything†, self-discipline, self- control is not as important as it was before. Teenage girls seem to be known to have the values of â€Å"teenage pregnancy†, while other teenagers have values of smoking weed, drinking, having a good time rather than having a good education, a future and moral values that will be needed to everyday life. On the other hand the positive values that are shown about teenagers are their families, education, respecting ourselves including our bodies, and some people might th ink this is bad but it could be a good thing, technology.Technology is growing every day and affecting everybody’s lives one way or another so the opinion that the teenager values technology all depends on the person’s thoughts. The social consequences of media portraying teenagers in this manner is that teenagers get a bad â€Å"image† and when someone sees a teenager now a days they will think they are up to no good, having no hope for the future generations including us and the generation after us. Teenagers have this â€Å"bad image† of being irresponsible, untrusted, and just unappreciated takes a toll on someone and they can act out and do the actions everybody expects them to do.Also what could happen is that with such a high expectation for somebody it can just be too much for that one person and that is where more problems can appear. Other social consequences that the media can contribute to is when on the TV, teenagers see these celebrities eat so much but yet have those â€Å"perfect† bodies that everybody seem to want, having commercials with models that look flawless when in reality they don’t look like that but of course the media doesn’t tell the audience that.The final discussion I want to talk about is the commercial factors that influence the media; the media mostly shows a Caucasian attractive person who is very confident and it seems to be that this â€Å"person† is in every TV show, commercial, movie, etc. The commercials that are shown in today’s society vary different objectives in the audience in what they want to sell or promote, it can be from a new smartphone (new technology) to a campaign about stopping bullying. The media is influencing the commercial factors by showing the audience of what â€Å"teenagers want† and what â€Å"teenagers need† as in help having a voice in bullying for example.The commercials can either show a positive look on teenagers or a negative look, normally the media has a little of both and that can influence a teenager either in a good way or bad. For example you see commercials that set awareness of drinking and driving or texting and driving giving teenagers a new outlook of what could possibly happen if they do these actions which in this case will leave a positive influence on teenagers in making the right choice. Commercial factors can influence teenagers, but in the end it all depends on the eenager and their thoughts and values. In the end, media does influence teenagers as it also portrays a good and bad image even if it’s realistic or not. The media has two sides of this, the â€Å"seen† and the â€Å"not seen† realities of teenagers, the values can be depicted by the audience if the teenagers values are true or not. The social consequences can vary but can be very serious with the media surrounding everybody every day and with the commercial factors that are also influenced by the media the teenager topic can either be looked at in a positive way or negative. Media Studies April 5, 2013Unit 3 – Lesson 14 – Key Question #30Keitlin Okell In today’s society the media can portray different â€Å"groups† in certain ways towards society. One of these groups are teenagers; the realities that are portrayed within this specific group can be very misunderstood or very accurate depending on what is â€Å"seen† and â€Å"not seen†, values are also constructed within the media around us as teenagers not valuing what was valued in the past generations.Finally with the different media surrounding everyone’s lives, the commercial factors do influence the media with the â€Å"teenager† topic with giving teenagers a bad image sometimes but however the commercial factors can give a positive look on teenagers. If people were asked what their first thoughts of when they heard the word â€Å"teenager†, the first thoughts that come to their mind will probably shock you, with it being; negative, wild, irresponsibl e, immortal, violent, monsters, etc. These type of thoughts that are constructed about teenagers come from the media and what is â€Å"seen† and â€Å"not seen†.What is seen in the media the â€Å"glamorous† lifestyles of teenagers that go out to drink, party, abuse alcohol and drugs, deal with violence, and other inappropriate actions; all these actions are shown within movies, TV shows (reality or not), newspaper and even music. An example is the movie â€Å"Mean Girls†, this movie is about cliches, and how the high school life â€Å"is†, with the lies, sex, drinking, and not showing the positives of being a teenager and the difficulties that every teenager goes through. The media doesn’t show the hard part of being a teenager such as being bullied, exams, stress and insecurities.Also what is not shown within the media about teenagers is that they do care about politics, society’s issues, the environment, volunteering, their school work and other positive activities. Realistic wise, the media over exaggerates the topic of being a teenager because the media thrives on scandals even if that includes over reacting the â€Å"life of a teenager†; this is to get the audiences reaction, awareness and entertainment all at once. The values that are represented about teenagers are right but are also wrong.The negative values that are represented for teenagers is that they don’t care about â€Å"anything†, self-discipline, self- control is not as important as it was before. Teenage girls seem to be known to have the values of â€Å"teenage pregnancy†, while other teenagers have values of smoking weed, drinking, having a good time rather than having a good education, a future and moral values that will be needed to everyday life. On the other hand the positive values that are shown about teenagers are their families, education, respecting ourselves including our bodies, and some people might th ink this is bad but it could be a good thing, technology.Technology is growing every day and affecting everybody’s lives one way or another so the opinion that the teenager values technology all depends on the person’s thoughts. The social consequences of media portraying teenagers in this manner is that teenagers get a bad â€Å"image† and when someone sees a teenager now a days they will think they are up to no good, having no hope for the future generations including us and the generation after us. Teenagers have this â€Å"bad image† of being irresponsible, untrusted, and just unappreciated takes a toll on someone and they can act out and do the actions everybody expects them to do.Also what could happen is that with such a high expectation for somebody it can just be too much for that one person and that is where more problems can appear. Other social consequences that the media can contribute to is when on the TV, teenagers see these celebrities eat so much but yet have those â€Å"perfect† bodies that everybody seem to want, having commercials with models that look flawless when in reality they don’t look like that but of course the media doesn’t tell the audience that.The final discussion I want to talk about is the commercial factors that influence the media; the media mostly shows a Caucasian attractive person who is very confident and it seems to be that this â€Å"person† is in every TV show, commercial, movie, etc. The commercials that are shown in today’s society vary different objectives in the audience in what they want to sell or promote, it can be from a new smartphone (new technology) to a campaign about stopping bullying. The media is influencing the commercial factors by showing the audience of what â€Å"teenagers want† and what â€Å"teenagers need† as in help having a voice in bullying for example.The commercials can either show a positive look on teenagers or a negative look, normally the media has a little of both and that can influence a teenager either in a good way or bad. For example you see commercials that set awareness of drinking and driving or texting and driving giving teenagers a new outlook of what could possibly happen if they do these actions which in this case will leave a positive influence on teenagers in making the right choice. Commercial factors can influence teenagers, but in the end it all depends on the eenager and their thoughts and values. In the end, media does influence teenagers as it also portrays a good and bad image even if it’s realistic or not. The media has two sides of this, the â€Å"seen† and the â€Å"not seen† realities of teenagers, the values can be depicted by the audience if the teenagers values are true or not. The social consequences can vary but can be very serious with the media surrounding everybody every day and with the commercial factors that are also influenced by the media the teenager topic can either be looked at in a positive way or negative.

Anti Federalists vs. Federalists

Anti Federalists vs. Federalists Anti-Federalist and Federalist Political Science American Government and Politics Professor Mike Connolly Anti Federalist vs. Federalists started after the Revolutionary war and the Americans had to figure out a way to get themselves out of economic depression because the war was costly and left many colonies in debt. Anti-federalists were those who opposed the development of a strong federal government and the Constitution in 1788, instead for power to remain in the hands of state and local governments. Federalists wanted a stronger national government and the ratification of the Constitution to help properly manage the debt and tensions following the American Revolution. People who supported the Anti-Federalist were people who lived in rural areas and had local power. People who supported the Federalist were rich people who lived in large rural areas. Basically middle class people supported the Anti-Federalist and rich people with businesses favored the Federalist. That is kind of similar to our current fight between power of government, for example Democrats vs. Republicans, Democrats favored people who are in the middle class and lower and Republicans favored people who are in the high class who are wealthy. The Anti-Federalist wanted to be like free agents they wanted to spend and manage their own money as they saw fit. They believed that no one should control the way they spend and control their money the Federalist were people who wanted the opposite. The debt and tension in Massachusetts known as the Shay’s Rebellion was a perfect example of why the U.S had the desire to concentrate on federal power. Before the constitution there were the Articles of Confederation, a 13 article agreement between 13 founding states that covered issues of the state sovereignty. The Articles of Confederation were mainly about the equal treatment of citizens, congressional development and delegation, international diplomacy, armed forces, fund raising, lawmaking, the relationship between the US and Canada and war debt. The problem with The Articles of Confederation was it was a very weak agreement on which to base a nation that the document never once referred to the United States of America. With The Articles of Confederation, congress became a form of Federal government, but it was weak by the fact that it could not fund any of the resolutions it passed. For example while people can print money, there was no solid regulation of the money, which led to a fast and deep depreciation. Though congress asked for millions of dollars in the 1780’s, they received less than 1.5 million over the course of three years, from 1781 to 1784. This inefficient and ineffective governance led to economic woes and eventual, if small scale, rebellion. As George Washingtons chief of staff, Alexander Hamilton saw firsthand that the problems caused by a weak federal government particularly those which stemmed from a lack of centralized fiscal and monetary policies. With Washingtons approval, Hamilton assembled a group of nationalists at the 1786 Annapolis Convention also known as the Meeting of Commissioners to Remedy Defects of the Federal Government. Here, delegates from several states wrote a report on the conditions of the federal government and how it needed to be expanded if it was to survive its domestic turmoil and international threats as a sovereign nation. After the Articles of Confederation cam the Constitution in 1788 where the Constitution replaced the Articles of Confederation, greatly expands the powers of the federal government. With their only being 27 Amendments, the US Constitution remains a supreme law of the United States allowing it to define, protect, and tax its citizens. Federalist who were the main support ers of the Constitution; they were aided by federalist sentiment that had gained traction across many factions, uniting political figures. The Anti-Federalist, who was leaded by Thomas Jefferson, fought against the Constitutions ratification, mainly the amendments which gave the federal government fiscal and monetary powers. The fight between the two groups the Federalist and the Anti-Federalist resulted in the upcoming of the Federalist papers and the Anti-Federalist papers, it was a series of handwritten essays from various figures for against the ratification of the Constitution and the protection of the Constitution. Among the Anti-Federalist were Thomas Jefferson and James Monroe. Jefferson was the leader among the Anti-Federalist and other prominent Anti-Federalist included Samuel Adams, Patrick Henry and Richard Henry Lee. For the Federalist side they had Alexander Hamilton a former chief of staff to George Washington, he was a proponent of a strong federal government and fou nded the Federalist Party. He helped oversee the development of a national bank and a taxation system. Other famous Federalist was John Adams and John Jay. There were also three kinds of Anti-Federalist, the first kind represented by politicians such as Roger Sherman and Oliver Ellsworth of Connecticut. The second kind of Anti-Federalist were the people who were not privy (a person having a part or interest in any action, matter, or thing) to the debate in Philadelphia, and has some concerns about the potentiality (the ability to develop or come into existence) of the Constitution to lead to the concentration of power in the new government. Third and final groups of Anti- Federalist were those who want as little deviation from the articles of confederation as possible and saw that partly national and partly federal compromise as totally unsustainable. Basically Anti-Federalist wanted a weak federal government that would not threaten state rights and wanted the Bill of Rights to declare and protect the rights of the people. During the Ratification the Federalists promise an addition of a Bill of Rights. The ratification succeeded and the new government was formed in 1789. James Madison was a Federalist or Democratic Republic who drafted the 10 amendments to the Constitution and these become the U.S Bill of Rights. Once again the Federalists believed that establishing a large national government was not only possible, but necessary to create a more perfect union by improving the relationship among the states. The Federalist also wanted to preserve the sovereignty and structure of the states, but to do so they advocated f or a federal government with delegated powers. Anything not delegated to the Federal government would be reserved to the people and the states. Their goal was to preserve the principle of government by consent, by building a government upon foundation of popular sovereignty, without sacrificing the sovereignty of the states. Present day it appears that the government established by the Constitution is an improvement from that which was established by the Articles of Confederation. Reading and writing about the confrontation between Federalist and Anti-Federalist I would have chosen the side of Federalist and I will explain why. Me Anti-Federalist were people who were scared of a strong government because they did not want the government to control their lives and wanted a little bit more freedom. Yes, people need their freedom but what they need more is to be secured and free from debt. The problem there was a economic struggle and people were in debt because of the war with Federalist we can have people manage the finances and economy. The Anti-Federalist sounded spoiled because they felt that the states were free agents that should manage their own revenue and spend their money as they saw fit. Many people back then probably were not well informed about their finances and might have spent money that they could not afford to get back. To be on the safer side a professional should be the one to see what a person is allowed to spend without getting themselves into debt. At the same time Anti-Federalist have a point because they should not have too much power to the point where they can deny a person from purchasing a item. Anti-Federalist sounds like it is the freedom fighter group for the people and they are a group who opposes to strong of a government but people should know to much freedom can cause many problems. The positive side of Federalism is the protection against tyranny, is dividing the power between the national government and state governments and spreading the national government’s power among three branches that serve as a check and balance on each other. The protections we have in our system against a tyrannical, runaway government are one of the most important points to why the system was designed the way it was. Increasing citizen participation is by not centralizing all power into the hands of a national government, but sharing that power with state governments, which are closer to the level of the common citizen; our founders actually increased a citizen’s ability to effect their government. Finally one more positive point is conflict management, by allowing different communities and states to create their own practices, they allow for people with differences or very strong disagreements, to live in separate areas, and create their own solutions, or policies, that would be totally disagreeable to the other people in other states or regions of the country. Citations: 1. Anti-Federalist vs Federalist. (n.d.). Retrieved December 14, 2017, from https://www.diffen.com/difference/Anti-Federalist_vs_Federalist 2. Federalists Vs. Anti-Federalists. (n.d.). Retrieved December 14, 2017, from https://apgovernmentchs.wikispaces.com/Federalists Vs. Anti-Federalists 3. Bardes, B. A., Shelley, M. C., Schmidt, S. W. (2018). American government and politics today: the essentials. Boston: Cengage Learning.

Con law 1 Essay Example | Topics and Well Written Essays - 750 words

Con law 1 - Essay Example The information also stated that some illegal betting equipment might also be present in that home. Mapp refused to allow them permission to enter and search the home as the police officers did not have a search warrant as required in law. The officers forcibly entered the home and searched it, without producing a search warrant to Mapp. As it turned out the officers did not find any of the things that they had come to search for, but instead they found some pornographic materials in the house. As a result, they arrested Mapp and charged her for being in possession of pornographic material, and later sentenced. At the trial, the prosecution did not produce a search warrant as evidence (Mapp v. Ohio. 1961). The Supreme Court upheld that evidence acquired illegally is inadmissible in State courts; since the law could not be properly upheld if illegally obtained evidence was to be admitted in court. This exception seemed as the most effective means of upholding professionalism of the po lice officers in execution of their duties. Even though there was concern on the basis that this rule may result in criminals going scot-free, it was obvious that upholding police professionalism, in some great extent, outweighed this concern. This case served as one of the significant cases that played a great role in re-evaluating the role of the fourth amendment in the judiciary (Mapp v. Ohio. 1961). Exclusionary Rule The general rule of the Exclusionary Rule is that any evidence gathered in violation of the fourth amendment is inadmissible in court. This rule states that if police officers contravene a person’s constitutional rights, in their pursuit of evidence, they cannot use that evidence against the person. The exclusionary rule serves as a very important remedy against improper searches by the police officers. It can be of great use in the general protection of the citizens’ rights. This rule is a creation of the court so us to uphold the Constitutional amend ments that were made. Courts are keen in applying the rule in order to exclude illegally obtained evidence where the costs of exclusion are greater than its deterrent or remedial benefits (Tomkovicz, 2009). The Supreme Court sets up the provisions of the Bill of Rights against the state on many occasions. The question that arises is whether the court will continue supporting the same principles imposed on the federal states against the State. Most of the court decisions are in support of this idea of using the same standards for both types of states (Tomkovicz, 2009). However, there are several exceptions to the general rule. These exceptions include non-trial criminal proceedings for example, bail proceedings, and a proceeding in revoking parole as an exception. It holds that constitutionally, there may be admission of evidence obtained illegally in such non-trial criminal proceedings. Another exception is the arraignment of the defendant. This exception enables the prosecutor to p roduce evidence illegally obtained from the defendant if only the purpose is to impeach the defendant. However, such evidence may be in-admissible for the purpose of impeaching other witnesses of the defense, as it was held in James v Illinois, 493 U.S 307 (1990). â€Å"Good faith† is also an exception of the general rule. It states that evidence obtained illegally by a police officer in belief that either the search does not require

Greece - National Technological Infastructure Step 2 Research Paper

Greece - National Technological Infastructure Step 2 - Research Paper Example According to the 2009 estimates, 6,779 barrels of oil were produced everyday in the country’s reserves. The oil in the reserves is estimated to be about 10 million barrels. Consumption of oil is high at 414,400 barrels per day. The country also imports 553, 000 barrels of oil every day (CIA World Factbook, 2010). Natural gas is also another source of the country’s energy and power, according to the World Factbook. There are several natural gas reserves in Greece which have an estimated 1.982 billion cu m of natural gas. The production rate of natural gas from these reserves is at 9 million cu m per year. The annual consumption of the same is at 3.528 billion cu m, which is way above the production level. This has made the Greek government to include the importation of 3.556 billion cu m of natural gas to take care of the deficit. Greece has also embarked on an ambitious program to increase the use of natural gas in different industries. One of the main energy development projects is the National Gas System (ESFA) which facilitates the transportation of natural gas in different regions in the country. Going by the present trends in the Greece energy and power sector, natural gas is increasingly becoming a common feature in industries, residential areas and in the commercial and public services sector. However, oil continues to account for more than half of all of the country’s energy and power usage. The transport and industry sector are the major consumers of oil in Greece. Electricity is also quite reliable in the commercial and public services sector as is the use of wind power in the smaller industries. There are plans to have wind power to account for about 15% of the country’s energy needs by the end of this year (World Factbook, 2010). The communications system in Greece is characterized by a network of landline telephones as well as mobile cellular communication. Greece has about 5.975 million main telephone lines which are in active

Multinational Enterprises and the Global Economy Essay

Multinational Enterprises and the Global Economy - Essay Example For instance, foreign direct investment is one such activity, which has influenced the overall relationship among various governments and international companies trying to enter the host nations. FDI will be studied as an extended example along with its pros and cons in various nations as well as host organizations. According to Peters and Pierre (2006), â€Å"globalization refers to the worldwide phenomenon of technological, economic, political, and cultural exchanges among nations, organizations and private individuals.† As a direct result of these exchanges, nations are more dependent on each other than ever. This has also resulted in interconnectedness and innumerable opportunities, in terms of modern technology, larger markets, superior and modern goods and services as well as minimum barriers to capital and trade flows. This has also changed overall wants, tastes, demands and needs of consumers, who are increasingly converging towards being called as global customers. Apart from opportunities, globalization is also filled with numerous challenges. These challenges include fierce competition, decline in the number of local job opportunities, close-down of various local organizations and even some retail formats, market liberalization, economic volatility, new and more complicated se curity issues as well as increased non-tariff trade barriers. So, it can be said that globalization has brought both positive and negative influences on the overall world economy as well as relationship between the host government and MNEs. The overall influence of globalization can be described in terms of two critical developments. Firstly, the re-occurrence of regional and economic proximity that contributes to enhanced investigation about innovation. The second development is the growing inter-relationship between innovation and technology. It has been observed that majority of innovations, occurring across sectors, are direct or indirect results of advancements in

Importance Of The Tea Party Movement Essay Example | Topics and Well Written Essays - 1000 words

Importance Of The Tea Party Movement - Essay Example Tea Party disrupts the political process and it does not help America move forward. Instead of contributing to the national government, it thoroughly muddles policymaking to the point of paralysis. It’s the reason for existence is redundant, echoing that of the Republican, although in a noisier and more populist manner not unlike the voice of the rabble. A core component of the argument that the Tea Party is not a helpful addition to American politics is the fact that it does not have a single uniform agenda. The leaders and organizers try to rationalize this by saying that such fragmentation and decentralization prevents the party from being co-opted and corrupted from within (Rauch 2010). But, unfortunately, this is not the case. The lack of leadership and unifying principles paved the way for divergent goals and priorities among the various groups that constitute the party. The result is raucous agenda that even confounded the very Tea Party members or those affiliated with the group. Consider, for example, the rally that some of Tea Party members staged amidst the debt limit deadline while the Senate is deadlocked and nowhere near the resolution of the crisis. The group converged on the World War II memorial on the National Mall and did some damage to some facilities before proceeding to stage their antics near the White House. As speaker after speaker spoke in unorganized fashion either on a platform or before television cameras, the different messages were vying for the public’s attention. At one point, someone was talking about the government closing down the national park. Then, an attendee interviewed by the members of the media covering the event was calling for civil disobedience, demanding that Obama is removed from office (Cooper 2013).

Attachments theory as it affects adolescants Essay

Attachments theory as it affects adolescants - Essay Example According to attachment theory, primary caregivers become increasingly differentiated from other people in the minds of infants during their first year of life. During childhood, adolescence, and adulthood, many individuals encounter difficulties in their relationships with parents and spouses that shake their confidence in the availability of these attachment figures. Such difficulties may fundamentally disrupt attachment bonds and dramatically reduce an individual's capacity to adapt to challenges outside the family. In the second volume of Attachment and Loss, Bowlby (1973) refined his definition of the set goal of the attachment system. In considering the effects of separations on children, he moved toward the notion that security derives from a child's appraisal of an attachment figure's availability (Bowlby, 1973). The child needs to experience a parent who is not only accessible but also responsive. This aspect of security incorporated Ainsworth's findings that it is the quality of day-to-day interactions, not just major separations, that influences infants' attachment expectations. In contrast, various nonresponsive or insensitive f orms of care can undermine the infant's confidence or even lead to expectations for rejection or inconsistent response. Separation distress results from the appraisal that a parent is inaccessible (Ainsworth et al., 1978). This perceived threat to a parent's accessibility activates the attachment system and motivates a child to reestablish contact. Emotional reactions accompanying the appraisal of threat include fear and anger. Fear activates the attachment system and signals the child's distress. Anger results from frustrations that the child encounters in trying to regain access, and it mobilizes efforts to reestablish contact. Adolescents The adolescent, by contrast, may act out her conflict about separating through fights with her mother and open defiance. Her upheaval may be more visibly apparent in her relationship with her mother, more provocative and dramatic. Girls may direct their acting out toward their bodies and engage in behaviors that are outside of the domain of parental control. They are at increased risk for eating disorders, reckless or promiscuous sexual activity, and self-cutting or other forms of mutilation. Adolescents may also use drugs and alcohol to rebel, explore, and escape painful feelings. Self-defeating or destructive behavior may provide an illusion of independence while also serving to defend against regressive longings. The thrill and power of reckless acting out can reduce their sense of vulnerability and distract from feelings of loss associated with the transition from childhood dependence. The attachment to a therapist can take pressure off the mother-daughter dyad, as some dependenc e needs are being met in a relationship outside the family. However, the stage is then set for the adolescent to recreate with the therapist elements of her struggle with her mother. Her dependence on the therapist can trigger resistance to treatment. Like the defiance at home, acting out within therapy may serve both to rebel against therapeutic influence and to pull for protective intervention (Cassidy et al., 2003). Similar patterns of maladaptation have been identified in adolescents and adults who are classified as

Analysis NASA Challenger Case Essay Example | Topics and Well Written Essays - 250 words - 1

Analysis NASA Challenger Case - Essay Example Administrators owe their loyalty to the employees, students, school districts and the parents. Employees rely on the information given to them by the administrators. In addition, parents have trusted the administrators to protect their children. Moreover, school districts have mandated the administrators to achieve laid down goals and objectives. Finally, students expect administrators to ensure their safety and quality service delivery to them. In order for the administration to protect their relationship with employees, they give this type of recommendation when getting rid of their employees. They give an employee a chance of another employment by another institution. In most cases friendship tend to have outdo honesty. Administrators tend to offer half-truths about their employees due to friendship. However, that not ought to be the case. Honesty in the workplace is fundamental, since it ensures that there is trust among the administrators. In addition, honest information makes one to make right decisions. In the Gadam’s case, the administrators said nothing about Gadam’s behavior. This may have been due to the friendship that existed between the administrators and Gadam. Moreover, due to the fear of tarnishing the reputation of the institutions by a negative recommendation letter about one of their employee. In the NASA case, the managers are fully responsible for the explosion. Despite their knowledge in engineering and the reasons the engineers gave against the launch, they adamantly gave an okay for the launch of the rocket. In addition, they decided to throw their engineering knowledge to the wind and embrace the management skills. I would have tried to persuade the managers not to launch the rocket, if I was in the position of McDonald or Boisjoly. Moreover, I could have warned the six astronauts and Christa McAuliffe about the danger they were about to get

Punctuality and Correct Medical Aid Essay Example for Free

Punctuality and Correct Medical Aid Essay The saying which goes A stitch in time saves nine is very true!!!Punctuality is no doubt a virtue no man can afford to lack. It is the simplest and easiest to acquire but at the same time really needed to succeed in life. Punctuality is the habit of doing things in time. It is a disciplinary force which contributes to the efficiency and success of both an individual and organization. A punctual person is always a step ahead of others . He is able to complete his assignments and keep commitments which wins him the command and respect of all those who work with him .He becomes an asset and support in any field of life. He will be a sought after member of any organization for the respect he has earned by his reliability and sense of discipline. Lessons of punctuality are introduced from the very birth of a child. Feeds are given punctually and so are medications. Schools , colleges also implement and enforce these in every possible way .Time tables, classes ,examinations all demand punctuality. A company which fails to deliver goods or services in time or is unpunctual in collecting dues is also bound to fail one day or the other. In hospitals on some occassions punctuality may make all the difference between life and death . Forgetting to give a medicine or injection on time may take a life! On the other hand bringing a patient and giving him the correct medical aid in time will save a precious life!History also shows how punctuality plays such an important role even in war. General Neys unpunctuality ruined Napoleon and changed the course of European history. If we study the lives of some great people we find that punctuality was one of the pillars of their success. Professionals like lawyers , doctors, teachers who have reached success are further respected when they keep their appointments and timely commitments . If we look around we shall see that sense of order and punctuality is seen in Nature too. The sun rises in the day , planets move in orbits, seasons keep their cycle teaching us the significance of time and punctuality in life. Today we live in a modern complex society where so many things are interdependent. It is essential for the smooth functioning that people recognise the need for punctuality. If trains and flights do not keep punctuality it can create such a mess and sometimes cause havoc and disaster or even accidents. In the age of rockets and moonlandings the importance of punctuality is felt even more. To organize events meetings and make them successful it is essential that all participants keep time and are punctual. Could big events like the Olympics be a success without punctualityWe should make a humble beginning and start incorporating punctuality in our lives in our day to day activities. Bed time and waking time , meal times if adhered to will help discipline us and tune our minds towards punctuality in other areas also. Once disciplined and punctual a very different future welcomes you. One would surely realise that punctuality is the key to success and greatness in life. One step at a time but always on time..!!!!

Hemoglobin Malaria Haemoglobinopathies

Hemoglobin Malaria Haemoglobinopathies Despite major advances in the understanding of the molecular pathophysiology and control and management of the inherited disorders of hemoglobin (haemoglobinopathies), thousands of infants and children with this disease are dying. As a result in heterozygote advantage against malaria the inherited hemoglobin disorders are the commonest monogenic disease. Population migrations have ensured that haemoglobinopathies are now encountered in most countries including the UK. Haemoglobinopathies have spread from areas in the Mediterranean, Africa and Asia and are now endemic throughout Europe, the Americas and Australia. This review examines the available literature to find out more about the prevalence of haemoglobinopathies in the UK. The data on the demographics and prevalence of the gene variants of haemoglobinopathies was extracted from books, journals, reference sources, online databases and published review articles from the WHO. Introduction It has been estimated that approximately 7% of the world population are carriers of such disorders and that 3000 000 4000 000 babies with severe forms of haemoglobinopathies. Haemoglobinopathy disorders occur at their highest frequency in tropical regions and population migrations have ensured that they are now encountered in most countries. Because of this, haemoglobinopathies have become a global endemic, so the World Health Organization published journals and reviews with recommendations on screening programmes and management of haemoglobinopathies. The programmes are tailored to specific socioeconomic and cultural contexts and aimed at reducing the incidence, morbidity and mortality associated with these diseases. www.who.int/en/ The WHO Executive Board wrote a review on haemoglobinopathies. In this article, the WHO Executive Board recognized that the prevalence of haemoglobinopathies varies between communities, and that insufficiency of relevant epidemiological data may hamper effective and equitable management of haemoglobinopathies. On this note England implemented the LIVE programmes. The Executive Board also recognizes that haemoglobinopathies are not yet officially recognized as priorities in Public Health Sector. This raised an issue about awareness of haemoglobinopathies. The WHO Executive Boards advice for prevention and management of haemoglobinopathies was to design, implement and reinforce in a systematic equitable and effective manner, comprehensive national, integrated programs for prevention and management of haemoglobinopathies, including surveillance, dissemination, such programs being tailored to specific socioeconomic and cultural contexts and aimed at reducing the incidence, morbidity and mortality associated with these diseases. www.who.int/en/ With immigration in the UK on its highest, the prevalence of haemoglobinopathies is expected to increase. The NHS has implemented programmes for individuals with haemoglobinopathies by implementation of LIVE program (NHS Plan, 2000). LIVE program is set-up to implement variant screening in the whole of UK by the year 2007. LIVE program started as early as January 2004 in high prevalence. The NHS Trusts involved are to offer variant screening by end of 2004/5 (NHS Plan, 2000). Low prevalence Trust are expected to have implemented the screening program by January 2008 and so far 86 out of 90 Trusts have successfully implemented the program. Antenatal and Newborn Screening programs have compiled a training pack to assist Low Prevalence Trusts with the implementation of haemoglobinopathies screening programmes. The NHS Plan (2000) made a commitment to implement effective and appropriate screening programs for women and children including a new national linked Antenatal and Newborn screen ing programs for haemoglobinopathies. The NHS Plan (2000) recommends that all pregnant women living in high prevalence areas are offered screening for haemoglobinopathies. All pregnant women living in low prevalence areas are offered screening for haemoglobinopathies. If a woman is identified as being at increased risk using the family origin questionnaire, she will then be offered screening for haemoglobinopathies (NHS Plan, 2000). The Low Prevalence Trust is where the fetal prevalence of sickle cell disease is less than 1.5 per 10 000 pregnancies. Low prevalence trusts are to offer screening for variants based on an assessment of risk determine by a question to women about their babys fathers family origin by the end of 2005/6 (NHS Plan, 2000). Background on Haemoglobinopathies Haemoglobin: is the oxygen carrying capacity of the blood and it is also a protein. Haem is iron containing pigment, while globin is made up of chains which are a globular tetrameric protein which accounts for 97.4% of the mass of the haemoglobin molecule (Tortora et.al., 2006) . The globin tetramer consists of four polypeptides which are two alpha (ÃŽ ±) chains and two non-alpha chains. The synthesis of ÃŽ ¶ and ÃŽ µ chains is done during the first 10 to 12 weeks of fetal life. Within the fourth to the fifth week of intrauterine life ÃŽ ± and ÃŽ ² chains are synthesized. The non-alpha is beta (ÃŽ ²), gamma (ÃŽ ³), delta (ÃŽ ´), epsilon (ÃŽ µ) zeta (ÃŽ ¶) chains. Haemoglobin transports oxygen from the lungs to all parts of the body and it gives blood its red colour (Fleming, 1982) Haemoglobin synthesis Haem and globin synthesis occur separately but in a carefully coordinated fashion. Globin synthesis is under the genetic control of eight functional genes arranged in two clusters, the ÃŽ ± globin gene cluster on chromosome 16 and the ÃŽ ² globin gene cluster on chromosome 11. The major haemoglobin in the foetus is HbF (ÃŽ ±ÃŽ ²) 2 and in adults HbA (ÃŽ ±ÃŽ ²) 2 (Fleming, 1982). Haemoglobin Structure The primary structure of haemoglobin is made-up of amino acid sequence of globin. And the secondary structure comprise of nine non-helical sections joined by eight helices; tertiary structure describes globin chain folding to form a sphere and the quaternary structure of haemoglobin describes the tetrahedral arrangements of the four globin subunits ( Fleming, 1982). The external surface of each folded globin is hydrophilic and the inner surface is hydrophobic, this protects the haem from oxidation, which is also why each haem chain sits in a protective hydrophobic pocket. In haemoglobin A, ÃŽ ± ÃŽ ² dimmers are held together strongly at the ÃŽ ±1 ÃŽ ²1 or ÃŽ ±2ÃŽ ²2 junction. The tetramer is held together much less tightly at the ÃŽ ±1 ÃŽ ²2 and ÃŽ ±2 ÃŽ ²1 contact areas (Fleming, 1982). Haemoglobin function Each haemoglobin molecule can carry four oxygen molecules. Oxygenation and deoxygenation are accompanied by molecular expansion and contraction via haem haem interaction (Bienz, 2007). Under physiological conditions, blood in the aorta carries about 19.5ml of oxygen per 100ml of blood. Upon entering the tissues about 4.5ml of oxygen are donated per 100ml of blood. 2,3-DPG is an important modulator of haemoglobin A oxygen affinity in red cells (Fleming, 1982). Haemoglobin disorder (haemoglobinopathies) Haemoglobinopathies is a hematological disorder due to alteration of a genetically defect, that results in abnormal structure of one of the globin chains of the haemoglobin molecule (Bienz, 2007). Haemoglobinopathies are any of a group of diseases characterized by abnormalities, both quantitative and qualitative in the synthesis of haemoglobin (Hb) (Bienz, 2007). Qualitative affecting the quality of haemoglobin e.g. Sickle cell disorder and quantitative affecting the amount of haemoglobin produced e.g. Thalassaemias. Most of them are genetically inherited but occasionally they can be caused by a spontaneous mutation. Haemoglobinopathies are the worlds most common monogenic autonomic and recessive disease in humans (Anionwu et.al., 2001). 2.1Haemoglobinopathies fall into two main types; There are two categories of haemoglobinopathies. The two categories are: qualitative and quantitative; Qualitative affecting the quality of the haemoglobin e.g. Sickle cell disorder. In this disease the globin structure is abnormal. Quantitative the haemoglobin structure is normal but the amount of haemoglobin produced is affected. e.g. alpha and beta thalassaemias (Bienz, 2007). History of haemoglobinopathies In 1910 Herrick wrote an article in it he used the term â€Å"sickle† to describe the shape of the red blood cells of a 20 year old medical student from Grenada. This student had consulted Dr Herrick in 1994 complaining of a cough, fever and Feeling weak and dizzy. He constantly had anaemia episodes, jaundice, chest complications as well as recurring leg ulcers on both ankles. When his blood was examined, his red blood cells showed a large number of thin, elongated, sickle shaped and crescent- shaped forms (Herrick, 1990). The name thalassaemia was coined by the eminent haematologist George Whipple in 1936 as an alternative to the eponymous ‘Cooleys anaemia. He wanted a name that would convey the sense of an anaemia which is prevalent in the region of the Mediterranean Sea, since most of the early cases originated there. Thalassaemia is derived by contraction of thalassic anaemia (from the Greek thalassa -sea, an none and anemia blood) (Fleming,1982). Origins and Geographic distribution of haemoglobinopathies Carriers are found in all parts of the world: people from the North Mediterranean (South Europe) coast are 1-19% carriers. People of Arab origin are over 3% carriers. In Central Asia 4-10% and in South East Asia, the Indian subcontinent and China 1-40% carriers (the very high rates in this part of the world are due to HbE). In the Americas, North Europe, Australia and South Africa the local population has very low carrier rates but thalassaemia is still present because of the significant immigration from high prevalence area (Anionwu et.al.; 2001). Sickle cell and thalassaemia disorder mainly affect individual who are descended from families where one or more members originated from parts of the world where falciparum malaria was, or is still endemic. Population with such ancestry include those from many parts of Africa, the Caribbean the Mediterranean (including southern Italy, Northern Greece and Southern Turkey), Southeast Asia and thalassaemia gene is much wider now due to the hi storical movements of at-risk populations to North and South America, the Caribbean and Western Europe (Livingstone 1985). The geographic distribution of the thalassaemias overlaps with that of sickles cell disease. This is because carriage of these abnormal genes affords some protection against malaria. Thus, being heterozygous for one of these conditions offers a selective survival advantage and increases the opportunity for these genes to be passed on (Campbell et.al.,2004) 4Types and terminology of sickle cell and thalassaemia There are various types of sickle cell and thalassaemia disorders. The thalassaemia syndromes include alpha and beta thalassaemia major as well as beta thalassaemia intermedia. Sickle cell disorders (or Fickle cell disease include sickle cell anaemia (Hb SS), Sickle haemoglobin C disease (Hb SC) ÃŽ ² disease and E beta thalassaemia (www.sickle-thalassaemia.org/sickle.cel.htm) 4.1Sickle Cell Disorder: affects the normal oxygen carrying capacity of the red blood cells. The red blood cell forms a crescent or a sickled shape when it is deoxygenated. The ‘sickled cells are unable to pass freely through capillaries; the sickle cells also get stuck in blood vessels forming clusters which block the blood vessels and the blood flow. They dont last as long as normal, round red blood cells, which leads to anemia. This results in a lack of oxygen to the tissues in the affected area, resulting in hypoxia and pain (sickle cell crisis). Other symptoms include severe anaemia, damage to major organs and infection (NHS Antenatal and Newborn; 2006). There are several types of Sickle cell disease. The most common are: sickle cell anemia (SS), sickle hemoglobin C disease (SC), sickle beta plus thalassaemia and sickle beta zero thalassaemia. Each of these can cause pain episodes and complications. HbSS sickle is due to two sickle cell genes (â€Å"S†), one from each parent. This is commonly called sickle cell anemia. An individual with sickles cell anemia have a variation in the ÃŽ ²-chain gene, which then causes a change in the properties of hemoglobin which results in sickling of red blood cells (www.sickle-thalassaemia.org/sickle.cel.htm) HbSc inherited one sickle cell gene and one gene from an abnormal type of haemoglobin called â€Å"C†. It is due to the variation in the ÃŽ ²-chain gene. An individual with this variant suffers from mild chronic haemolytic anaemia. (NHS Antenatal and Newborn; 2006). HbS beta thalassaeamia: This form of sickle is due to inherited one sickle cell gene and one gene for beta. 4.2Thalassaemias: is a term used for the description of a globin gene disorders that results from a diminished rate of synthesis of one or more globin chains and a consequently reduced rate of synthesis of the haemoglobin or haemoglobins of which that chain constitutes a part ; ÃŽ ± thalassaemia indicates a reduced rate of synthesis of the ÃŽ ± globin chain, similarly, ÃŽ ², ÃŽ ´, ÃŽ ´ ÃŽ ² and ÃŽ µ ÃŽ ³ ÃŽ ´ ÃŽ ² thalassaemia indicate a reduced rate of synthesis of the h, ÃŽ ´, ÃŽ ´, +ÃŽ ² and ÃŽ µ + ÃŽ ³ + ÃŽ ´ + ÃŽ ² chains, respectively (Modell et.al, 2001). Thalassaemia is the most common single gene disorder known. It is autosomal recessive syndromes, which is divided into ÃŽ ±- and ÃŽ ² thalassaemia. Types of thalassaemia There are two types of thalassaemia: (i)Thalassaemia minor (thalassaemia trait) (ii)Thalassaemia major Thalassaemia minor is when a person inherits one thalassaemia gene, while thalassaemia major is a severe form of anaemia if a person inherits two thalassaemia genes, one from each parent (Bienz, 2007). Subtypes of thalassaemia Alpha (ÃŽ ±) thalassaemia results from inadequate production of ÃŽ ± chains, which are normally controlled by two pairs of chromosomes. If one or two are malfunctioning, then there is a healthy carrier state. If three are non- functional then anaemia results, known as HbH Disease, which can be quite severe but usually does not need blood transfusions and is compatible with a normal life span (Anionwu et al, 2001). If all four genes are non functional then the result is severe anaemia of the unborn child, leading to heart failure and death (miscarriage). This condition is known as hydrops felalis (Fleming, 1982). Beta (ÃŽ ²) Thalassaemia is caused by the bodys inability to produce normal haemoglobin, leading to a life threatening anaemia (Bienz, 2007). The severity of illness depends on whether one or both genes are affected and the nature of the abnormality. If both genes are affected, anemia can range from moderate to severe. Beta thalassaemia results from inadequate or lack of production of ÃŽ ² chains (Anionwu et.a.l, 2001). Homozygous, ÃŽ ² thalassaemia has two forms: major, in which the patient can survive only with regular transfusions of blood and intermedia in which the patient can survive with occasional or even with no transfusions at all. The condition requires frequent blood transfusions and treatment to prevent complications from iron overload, such as diabetes and other endocrine disorders (Anionwu et.a.l, 2001). Both of these conditions can restrict a child or adults ability to conduct their normal daily activities and can have profound psychological affects on individuals a nd their families This form of thalassaemia is the most important and constitutes a major public health problem in many parts of the world, because of the high frequency of carriers and the demanding treatment that must be followed (Fleming, 1985). Association of Haemoglobinopathies with Malaria Malariais a vector borne infectious disease caused by protozoan parasites. It is widespread in tropical and subtropical regions, including parts of the Americans, Mediterranean, Asia and Africa. It causes diseases in approximately 515 million people and kills between one and three million people, the majority of whom are young children. Malaria parasites are transmitted by female Anopheles mosquitoes. The parasites multiply within red blood cells, causing symptoms that include symptoms of anemia (Campbell et al, 2004). Sickle cell developed as a by product of human defense mechanisms against malaria. The most severe form of malaria, falciparum malaria, leads to very high death rate in young infants. This is particularly a problem between the time immediately after birth, when they are protected by immunity from the mother, and the time when they are old enough to acquire their own immunity. Malaria is a parasite which lives within the red blood cells and feeds off the protein that is contained within those red cells, haemoglobin (Campbell et al, 2004). When the malarial parasite enters the blood stream through a mosquito bite, it penetrates the red blood cells by attaching to the outside membrane or envelope of the red blood cell and gaining entry (Franklin, 1990). Once in the red blood cell, the malarial parasites use the haemoglobin as a source of energy, so that they multiply within the red cells. The parasites multiple filling-up the red blood cells and once they are filled-up the red cells bur st, thereby releasing the multiple parasites in the blood. Each new young parasite enters a single cell again and multiplies again, thereby causing a disease or infection. Whenever the parasites burst out of the cells they cause illness and fever in patients. Malaria can be severe by causing death; death is believed to be caused by red cells not being able to pass through the narrow gaps in the smallest blood vessels and by blockage of tissues when so many parasites are in the red blood cell (Campbell et al, 2004). Over the years human genes developed ways to prevent malaria becoming serious and potentially lethal, the developments were to prevent malarial parasites from spreading and multiplying (Tortora et.al,2006). The most changes were changes (mutation) in the type of haemoglobin (haemoglobin S) within the red blood cell which would in turn slow down the multiplying of the parasite (Campbell et al, 2004). The individuals with haemoglobin S are known to have a sickle cell trait or being carriers of sickle cell haemoglobin. When sickle-cell haemoglobin has given up its oxygen in the cells, the red cells stick together to form crystalline groupings of haemoglobin known as polymers. The red blood cells become deformed into sickle shapes and the presence of these crystalline polymers within the red cells inhibits the growth of the malarial parasite (Beinz, 2007). Even though individuals with haemoglobin S stills suffer from malaria, they are protected from the most severe effects of malaria (Li vingstone, 1985). Diagnosis Diagnosis for sickle cell disease The most used diagnose test for sickle cell is the haemoglobin electrophoresis. HbS and HbC amino acid substitutions change the electrical charge of the protein, the migration pattern of the haemoglobin with electrophoresis or isoelectric focusing results in diagnostic patterns with each of the different haemoglobin variants. HbSBeta-thal requires careful evaluation of red blood cell count and mean corpuscular red cell volume (MCV) and specifically quantifying HbA, S, A2 and F. In emergency setting, the presence of HbS is detected using a five minute solubility test called sickledex. Sickledex test does not differentiate sickle syndromes from the benign carrier state (HbAS or a sickle trait (NHS Antenatal and Newborn; 2006). Diagnosis for thalassaemias When testing for thalassaemias, a blood test is the simplest and most effective test for diagnosis and also the use of a test called Haemoglobin Electrophoresis. The blood of individuals with thalassaemias tend to be microcytic (smaller in size) and hypochromic (paler in colour) (NHS Antenatal and Newborn; 2006). 7 Pathophysiology 7.1Sickle-cell Sickle-cell anemia is caused by changes (mutation) in the structure of the ÃŽ ² -globin chain of the haemoglobin replacing the amino acid glutamic acid with the less polar amino acid valine at the sixth position of the ÃŽ ² chain. When two wild type ÃŽ ±-globin subunits associate with two mutant ÃŽ ²-globin subunits forms hemoglobin S. Haemoglobin S polymerizes under low oxygen conditions, which causes distortion of red blood cells and also causes red blood cells to lose their elasticity, resulting in red blood cells forming an irreversible sickle shape (Fleming,1982). Very often a cycle occurs, as the cells sickle they cause a region of low oxygen concentration which causes more red blood cells to sickle. Repeated occurrence of sickling causes cells to not return to normal even when oxygen levels are normal. The deformation of cells makes it difficult for the cells to pass through capillaries resulting in vessel occlusion, severe anemia, ischemia and other problems (Beinz, 2007). 7.2Thalassaemias The pathophysiologic effects of the thalassaemias range from mild microcytosis to death in uterus. The anaemia manifestation of thalassaemia is microcytic hypochromic haemolytic anaemia (Belcher, 1993). The haemoglobin abnormality is caused by substitution of a single amino acid for another; or substitution of two amino acids, also amino acid deletion or fusion (point of mutation) and the synthesis of elongated chains. In alpha trait, one of the genes that form the alpha chain is defective (Beinz, 2007). In alpha-thalassaemia minor, two genes are defective and in haemoglobin H disorder, three genes are defective. Alpha-thalassaemia major is most fatal thalassaemia disorder; this is because four of the chains forming genes are defective. Without alpha chains, oxygen cannot be released to the tissues (Belcher, 1993). In beta-thalassaemia haemoglobin abnormality is due to the uncoupling of alpha and beta-chain synthesis. This causes a depression in beta-chain synthesis, resulting in er ythrocytes with a reduced amount of haemoglobin and accumulation of free alpha chains, which are unstable and easily precipitate the in cell (Bienz, 2007). 8.Causes Genetic control of haemoglobin synthesis The synthesis of structurally normal haemoglobin chains is determined by allelic genes situated on the autosomal chromosome (Beniz, 2007). Haemoglobinopathies occur due to an inheritance of one or more faulty copy of gene(s) that contain the information for the cells to make the globin chains. The gene may result in abnormality in the production or structure of the haemoglobin protein causing haemoglobinopathies (Franklin, 1990). Thalassaemia is an inherited autosomal recessive blood disorder. Genetic defects in Thalassaemia results in reduced synthesis of one of the globin chains which make up haemoglobin. Reduced synthesis of one of the globin chains causes the formation of abnormal haemoglobin molecules, which in turn causes anaemia. Anaemia is a symptom of the Thalassaemias. It is caused by under production of globin proteins, often through mutations in regulatory genes (Franklin, 1990). Inheritance of Haemoglobin Disorder Due to haemoglobin mutation, individuals who had haemoglobin trait had a resistance to dying from malaria, therefore passed on their haemoglobin trait gene to their children (Campbell et.al,2004). As time went on more individuals with the trait were born and eventually individuals who had haemoglobin trait had children together (Franklin, 1990). In that satiation (partnership), if both parents carry the trait gene, there is a one in four chance that any one child will receive the haemoglobin trait gene from one parent and also from the other, thereby having a haemoglobin disorder(Franklin, 1990) . Clinical Manifestations 9.1Thalassaemias clinical manifestations Individuals who inherited the alpha trait are usually asymptomatic, with possible mild microctyosis. Alpha- thalassaemia minor has signs and symptoms almost identical to those of beta-thalassaemia; mild microcytic hypochronic anemia, enlargement of the liver and spleen, and bone marrow hyperplasia (Belcher, 1993). Alpha- thalassaemia major cause hydrops fetalis and fulminana intrauterine congestive heart and liver, edema and massive ascites. The disorder usually is diagnosed post mortem (Bienz, 2007). Beta-thalassaemia minor causes mild to moderate microcytic-hypochronic anemia, mild splenomegaly, bronze coloring of the skin, and hyperplasia of the bone marrow. Skeletal changes depend on the degree of reticulocytosis, which in turn depends on the severity of the anaemia (Bienz, 2007). People who have beta-thalassaemia minor usually are asymptomatic, whereas those with beta- thalassaemia major the anemia is severe, resulting in a great cardiovascular burden, with high output congestive heart failure (Belcher, 1993). Blood transfusions can increase the persons life span by a decade or two. Individuals with beta-thalassaemia major have an enlarged liver and spleen, and growth and maturation are retarded (Belcher, 1993). A characteristic deformity develops on the face as the bones expand to accommodate hyperplastic marrow (Belcher, 1993). Both and beta thalassaemias major are life threatening. Children with thalassaemia major usually are week, fail to thrive, how poor development and experience cardiovascular compromise with high-output failure; if the condition goes untreated, these children die by 6 years of age (Modell et.al., 2001) Blood transfusions can return haemoglobin and hematocrit to normal levels, alleviating the anaemia induced cardiac failure. Iron overload and hemochromatosis, which are complications of transfusion therapy, are treated with chelating agents (Bienz, 2007). . 9.2.Sickle-cell clinical manifestations The severity of sickle cell disorder depends on the amount of haemoglobin S and the clinical manifestations, which are signs and symptoms of the individuals with sickle-cell (Belcher, 1993) . Manifestations of the sickling are those of hemolytic anemia; pallor, jaundice, fatigue and irritability. Extensive sickling can precipitate four types of crises: vaso-occlusive or thrombotic crises and a plastic crisis (Belcher, 1993). A vaso-occlusive crises begins with red blood cells sickling in the microcirculation. Vasospasm brings a log-jam effect causing blood flow to stop flowing in the vessels and this will lead to thrombosis (blood clot formation) and infarction of local tissue occur, resulting in ischemia, pain and organ damage (Modell et.al.,2001). Vaso-occlusive crisis is believed to be extremely painful and lasts an average of 4 to 6 days. This crisis may develop spontaneously or may be precipitated by localized hypoxemia (low PO2) exposure to cold, dehydration, acidosis (low pH), or infection. In infancy, sickle-cells first manifestation is the symmetric painful swelling of the hands (see Fig 3) and feet, but in older children and adults, the large joints and surrounding tissues become swollen and painful. Individuals with the sickle-cell disorder suffer from severe abdominal pain caused by infarction in abdominal structures (Belcher, 1993). Any cerebral vascular accidents may cause paralysis or othe r central nervous system deficits, and if penile veins are obstructed priapism may occur. Studies have shown that bone, especially weight- bearing bones, are also a common target of vaso-occlusive damage, this is due to bone ischemia (Bienz, 2007). The spleen of individuals with sickle-cell disorder is frequently affected due to its narrow vessels, functions in clearing defective red blood cells and this results in a sequestration crisis (Belcher,1993). A sequestration crises, is occurrence of large amounts of blood pool in the liver and spleen. It only occurs in young children and death results from cardiovascular collapse (NHS Antenatal and Newborn,2006). An aplastic crisis develops when a compensatory increase in erythropoiesis is compromised; this then results in profound anemia (Belcher,1993). A hyperhemolytic crisis is rare but may occur with certain drugs or infections. G-6-PD deficiency, when also present, contributes to this type of crisis (Belcher,1993). Clinical manifestations of sickle cell disease do not usually appear until an infant is at least 6 months old. The most cause of death in individuals with sickle-cell anemia is infections, but it is major problem at all ages. Infections are due to splenic dysfunction from sickle damage (Belcher,1993). This occurs from a few months of age especially with certain bacteria e.g. pneumococcal sepsis. Infection tends to rapidly overwhelm the immune system (NHS Antenatal and Newborn,2006) . Sickle-cell haemoglobin C is known to be milder, with symptoms related to vaso-occlusive crises resulting from higher hematocrit and blood viscosity. Obstructive crises cause sickle cell retinopathy is most common in older children, and this include renal necrosis, and aseptic necrosis of the femoral head (Belcher, 1993). The mildest of sickle-cell is the sickle-cell thalassaemia the individuals with this form of sickle-cell tend to be microcytic and hypochromic, which makes the cells less likely to clog the microcirculation even when sickling (Belcher, 1993). Severe hypoxia can be seen in individuals with the sickle cell trait and may cause vaso-occlusive episodes. The cells in these people form an ivy shape (Belcher, 1993). Recent studies have shown that stroke is co-exiting with Sickle cell disease. At least 1% of patients with sickle cell disorder suffer from stroke and those individuals result in physical disability, IQ reduction, Learning difficulties, TIAs and seizures (Beinz, 2007). Treatment of haemoglobinopathies. 10.1Treatment in Sickle-cell anemia. Febrile illness: Children with fever are screened (a full blood count, reticulocyte count and blood culture taken) for bacteremia. In young children the fever is treated with intravenous antibiotics, the children would be admitted at the hospital so that they can be monitored (Belcher, 1993).. But older children with reassuring white blood cell counts are managed at home with oral antibiotics, but if the older children have a history of bacteremia episodes, they get a hospital admission. (Modell et al, 2001) Zn administration: is when zinc is given to stabilize the cell membrane (Beinz, 2007). Painful (vaso-occlusive) crises: individuals with sickle cell disorder experiences painful episodes called vaso-occlusive crises. Vaso-occlusive crises is often treated symptomatically with analgesics (Beinz,2007). Pain management requires opioid administration at regular intervals until the crises has gone. The frequency, severity and duration of these crises episodes vary tremendously form episodes to episode or from person to person (Belcher,1993). Individuals who suffer from milder vaso-occlusive crises manage their pain on NSAIDs e.g. diclofenac or naproxen. And if the crises is severe, individuals require inpatient management, where intravenous opioids. Diphenhydramine is used to stop the itchiness associated with the opioids (Modell et al, 2001). Acute chest crises management is similar to vaso-occlusive crises treatment with the addition of antibiotics, oxygen supplementation for hypoxia, and close observation. If the pulmonary infiltrate worsen or the oxygen requirements increase,

Custom Term Papers: Hamlet’s Heroine, Ophelia -- GCSE English Literatu

Hamlet’s Heroine, Ophelia In Shakespeare’s tragedy Hamlet there is, technically, no heroine. But the female character who comes closest to qualifying for the role is not Gertrude, whose sinful past precludes this, but rather Ophelia, the â€Å"universal victim† of the drama. She is truly a good, upright person although she is victimized by her father, brother and boyfriend. Harry Levin, in the General Introduction to The Riverside Shakespeare, elaborates on the special kind of prose which the dramatist uses with Ophelia when she suffers her madness: Though there is no invariable rule, the comic scenes are frequently in prose, whereas the tragic scenes are usually in verse. Yet some of the most tragic, notably Ophelia’s made scenes and the sleep-walking scene of Lady Macbeth, are in that special kind of distracted prose which Shakespeare reserved for moments of mental distraction, when the fragments of suppressed emotion well up from the unconscious. (11) Shakespeare’s use of distinctive language is one consideration concerning Ophelia. Another is her victimization. Gunnar Boklund in â€Å"Hamlet† performs a partial-analysis on the character of Ophelia in Shakespeare’s tragedy, Hamlet: The only character who is presented almost entirely as a victim is Ophelia, a victim of the King’s fear and curiosity, her father’s servility and fundamental indifference to her, Hamlet’s misunderstanding of the situation and brutal treatment of her, and finally his fatal thrust through the arras in the closet scene. Her madness is, as I see it, a purely pathetic element in the play. In the world where Hamlet has been forced to act, there appears to be no room for passive and obedient innocence. It is crushed, and perishes. (123) The p... ...: Madness Her Only Safe Haven.† Readings on Hamlet. Ed. Don Nardo. San Diego: Greenhaven Press, 1999. Rpt. from â€Å"Hamlet†: A User’s Guide. New York: Limelight Editions, 1996. Pitt, Angela. â€Å"Women in Shakespeare’s Tragedies.† Readings on The Tragedies. Ed. Clarice Swisher. San Diego: Greenhaven Press, 1996. Excerpted from Shakespeare’s Women. N.p.: n.p., 1981. Shakespeare, William. The Tragedy of Hamlet, Prince of Denmark. Massachusetts Institute of Technology. 1995. http://www.chemicool.com/Shakespeare/hamlet/full.html Ward & Trent, et al. The Cambridge History of English and American Literature. New York: G.P. Putnam’s Sons, 1907–21; New York: Bartleby.com, 2000 http://www.bartleby.com/215/0816.html Wilkie, Brian and James Hurt. â€Å"Shakespeare.† Literature of the Western World. Ed. Brian Wilkie and James Hurt. New York: Macmillan Publishing Co., 1992.

Shakespeares Othello - Desdemona the Ideal Essay -- Othello essays

Desdemona the Ideal  Ã‚        Ã‚  Ã‚   What wife can compare to the ideal wife which the Bard of Avon has painted for us in his tragedy Othello? She is appreciated by everyone except the villain.    Angela Pitt in â€Å"Women in Shakespeare’s Tragedies† comments on Desdemona as the ideal wife:    Handbooks of the period explain in some detail what is required of the ideal wife, and Desdemona seems to fulfill even the most conservative expectation. She is beautiful and also humble:    A maiden never bold Of spirit so still and quiet that her motion Blushed at herself. (I.iii.)    Her concern for Cassio shows her generosity, for she will intercede for him with Othello. She is wise, and also a ‘true and loving’ wife – ‘the sweetest innocent that e’er did lift up eye’. (44-45)    David Bevington in William Shakespeare: Four Tragedies describes the depth of virtue within this tragic heroine:    We believe her [Desdemona] when she says that she does not even know what it means to be unfaithful; the word â€Å"whore† is not in her vocabulary. She is defenseless against the charges brought against her because she does not even comprehend them, cannot believe that anyone would imagine such things. Her love, both erotic and chaste, is of that transcendent wholesomeness common to several late Shakespearean heroines [. . .]. Her â€Å"preferring† Othello to her father, like Cordelia’s placing her duty to a husband before that to a father, is not ungrateful but natural and proper. (221)    Blanche Coles in Shakespeare’s Four Giants interprets the protagonist’s very meaningful four-word greeting to Desdemona which he utters upon disembarking in Cyprus:    Othello’s four words, â€Å"O, my soul’s joy,† tel... ...mind behind the murder results in Iago’s murder of her. Gullible Othello, grief-stricken by remorse for the tragic mistake he has made, stabs himself and dies on the bed next to his wife, his sorrow being as deep as his love for Desdemona prior to Iago’s machinations.    WORKS CITED    Bevington, David, ed. William Shakespeare: Four Tragedies. New York: Bantam Books, 1980.    Coles, Blanche. Shakespeare’s Four Giants. Rindge, New Hampshire: Richard Smith Publisher, 1957.    Pitt, Angela. â€Å"Women in Shakespeare’s Tragedies.† Readings on The Tragedies. Ed. Clarice Swisher. San Diego: Greenhaven Press, 1996. Reprint from Shakespeare’s Women. N.p.: n.p., 1981.    Shakespeare, William. Othello. In The Electric Shakespeare. Princeton University. 1996. http://www.eiu.edu/~multilit/studyabroad/othello/othello_all.html No line nos.      

The Cultural Invasion of Kenya Essay -- American Culture Traditions Es

The Cultural Invasion of Kenya A screeching yell ripped through the house that Wednesday evening, "Ahhhhh, we're being invaded!". My mother rushed into the living room. I pointed to the flickering television screen. "Look," I whispered in disbelief. A few seconds of silence followed. There they were, the words I never thought would appear on our 29 inch Sony screen: "Sizzlin' Hot Country". The appearance of American country music on the Kenyan airwaves was the latest sign that American culture had penetrated the borders of my country. The airing of Garth Brooks and Dolly Parton on the local television station is not the only evidence of the rapid spread of American culture in Kenya. One look at a large portion of its youth and this cultural invasion will become apparent. Baggy pants, Nike, pop music and malls, symbols of American youth culture can now be associated with the Kenyan teenagers. The Nike phenomenon hit Kenya several years ago. My classmates in primary school were obsessed with the American brand name that had rocked the global shoe industry. Their school desks had the Nike name and logo painted on in every color imaginable. Not being able to afford some of the merchandise, many resorted to drawing the logo on bags, clothes, shoes and other visible possessions. Turning up to a class party with the trademark tick appearing on one's footwear simply made one the center of attention. My favorite pair of shoes, I have to admit, were a pair of black Nikes which raised many brows and turned just as many heads. Secondary school had its fair share of examples of the cultural invasion. In most schools in Kenya, students dress in uniforms. For example, in my school it was compulsory to wear a white shirt, gra... ...ols of success. While hip hop and baggy pants may not epitomize American success, Kenyan youth adopt this aspect of American culture perhaps because of the common roots and racial background the majority share with African Americans. Wearing Nike shoes or sagging one's pants may seem to be meaningless gestures. However, wearing shoes that many popular, rich American sporting icons don or sagging pants like the famous hip hop artists makes one different from the rest. It allows one to adopt an American identity, one defined by success and importance. While some would argue that such a spread of American culture would be beneficial because it would, in a sense, create a global village, I think this cultural invasion creates more harm than good. It would result in the demise of local cultures and languages. And this is certainly not a good thing.

Ethics and Morality Essay

There is an inherent question on the basis of morality and whether or not it is a man-made, almost religious invention or if it is intrinsic to our beings as humans. I think that the rope that is the argument between is too complicated and tightly knotted to have a short conversation about, but by fraying the ends of the rope we can inevitably decide that morality is innate and that religion may have a part in building upon it, but not in creating it. The curiosity behind the topic of morality is normally fashioned by religious arguments for the assumption that a deity endowed us as humans with some sort of moral compass. However, by searching the brain for its different functions and activities during moral dilemmas and religious interactions, along with historical clues and a little knowledge of sociology, determining that morality is not created, only built upon, is inevitable. Morality is defined as normatively to refer to a code of conduct that, given specified conditions, would be put forward by all rational persons (Stanford). With this as a definition, the first question to rises is the following: What is one moral action that a believer can do that a non-believer cannot do? There are few answers to the inverse, if any, but non-believers do not pose that they have any stronger of a moral compass than believers, while believers do. It is incredibly important to think about an answer to this question because if there truly is no answer to this challenge, then a road has been paved toward an objective that we can already see, which is that being ethical and moral is not necessarily a religious view, so such claims can immediately be cast off and the topic can stay on a strictly scientific road. Now the consideration lies upon what is deemed as an ethical person. Is the president ethical in his decisions? Is a doctor ethical in his decisions? Of course, there is an ethical code in these circles, but does that immediately mean that any decisions outside of the codes are immoral? A moral person is normally described as somebody who takes into account the possible consequences of his or her actions and rationally decides on a choice based on how it may affect those around him. We call these people morally good because their contributions to whomever they are around are normally well thought-out, harmless contributions to the topic. However, this is simply a definition, and the person is simply his or her self. Take into account the thoughts of those around the subject. A religiously-convicted man would say that his religion is the reason for his good nature, while one not necessarily supporting religion would say that he is simply a good person. As an aside, there are multiple people who would take the chance to point out many historically immoral figures, such as Mao Zedong, Stalin, Pol Pot, who were atheistic. While it is true that these figures were indeed non-believers, it is important to distinguish the reasons for their immorality. It was not based on religion, but rather by social constructs and a greed for power that caused them to act out. Some may cite Hitler as an atheist as well, but they’d be digging their own grave. Hitler, in Mein Kampf, even gives credit to the Christian god, and had religious inscriptions on every Nazi-uniform belt. To get back to the previous point, it is important to take into account what those around the subject would perceive, and although the religiously-convicted man might have millions of people around the world following his train of thought, research done Dr. Pyssiainen and Dr. Hauser from the departments of Psychology and Human Evolutionary Biology at Harvard University offers an interesting perspective on the topic: â€Å"†¦Despite differences in, or even an absence of, religious backgrounds, individuals show no difference in moral judgments for unfamiliar moral dilemmas. The research suggests that intuitive judgments of right and wrong seem to operate independently of explicit religious commitments. † Pyssiainen’s and Hauser’s study grants us that although religious backgrounds may indeed build upon moral constructs, as good religion is only positively influential to a good person, a complete lack of religious background is perfectly plausible if an individual wishes to be moral because moral judgments are not linked to religious commitments. This finding is absolutely crucial to determining whether or not morality is man-made or inherent to humans because it breaks the perceived bond between belief and morality. So their contribution to the topic has been seen through and accepted as a welcome source of reference. However, it is essential to look at the other side of the argument. Which studies show that seem to show that religion is a key factor in morality? Unfortunately, they are found few and far between. As a matter of fact, there are literally no scientific studies that show religion is crucial in the formation of morality. It’s widely granted that religion, in some aspects, can further construct upon morality and cause others to be exceedingly altruistic and generous, and that is conceded by Paul Bloom of Yale University, but it is not a formative agent. In his paper, â€Å"Religion, Morality, Evolution,† he accepts that religion can be a guiding influence on a positive path. However, he points out that it is by no means the reason for morality, and that religion itself may just be an accident by which humans needed an answer to questions that they couldn’t fathom without the help of a deity. Necessity dictates that there should be some rather fueled individuals on a topic as flammable as the topic of morality and religion. Speaking as an outsider looking in, I cannot very well use the words of Christopher Hitchens, though I would love to dearly, because he was so against religion. While he was indeed logical in most of his claims, he was a self-described anti-theist, meaning that he was against a spectating deity who watched over each individual. Thus, his words would seem rather biased. However, Richard Dawkins, an evolutionary biologist, and Sam Harris, a well-known neuroscientist, are individuals who speak strictly through logical and provable means. Richard Dawkins posed the same point as Paul Bloom that religion is most likely an accident through evolution that was used as a possible answer to the world’s greatest questions, and Harris poses multiple reasonable points. The most relevant, though, is that if the bible were the only book in the world, it would be rational to use it as a basis for morality. However, because the bible is not the only book in the world and society is far more civilized now than it was when the bible was conceived, it is reasonable to assume that the bible is not the best book for building a moral compass. To end on a rather short note, there are few, if any, scientific studies arguing that religion is the factory that builds moral compasses. However, there are studies being conducted which follow Pyssiainen’s and Hauser’s and should end up corroborating their finds that morality works independently of religious constructs and confines. Thus, it is both rational and reasonable to assume that, after looking through history at the reasons for extreme wrongdoings and the social situations that facilitated them, and the evidence against opposing claims, morality is indeed intrinsic to our human nature and that it is simply augmented by outside forces, such as good religion. References Bloom, Paul, Religion, Morality, Evolution (January 2012). Annual Review of Psychology, Vol. 63, pp. 179-199, 2012. Available at SSRN: http://ssrn. com/abstract=1982949 or http://dx. doi. org/10. 1146/annurev-psych-120710-100334 Cell Press (2010, February 9). Morality research sheds light on the origins of religion. ScienceDaily. Retrieved May 12, 2013, from http://www. sciencedaily. com /releases/2010/02/100208123625. htm Harris, Sam. Letter to a Christian Nation. New York: Random House, Print. Harris, Sam. The End of Faith: Religion, Terror, and the Future of Reason. New York: W. W. Norton, Print. Pyysiainen, Hauser et al. The origins of religion Q1 : evolved adaptation or by-product? Trends in Cognitive Sciences, February 8, 2010 â€Å"The Nature of Morality and Moral Theories. † Morality and Moral Theories. University of San Diego. Web. 12 May 2013. .

Nina

childrens needs February 2012 | | |Assignment 1: | |Explain what constitutes the physical and psychological needs of a three year old child. Explain how you would ensure that these physical and | |psychological needs can ideally be met in a setting/nursery which the 3 year old child attends from 8 am to 6 pm, 5 days a week. Reading for your assignment. Though we provide some recommended books and chapters, (see below) you need to read around the subject as much as possible and not limit yourself to just the recommended readings. Recommended reading from your prescribed text books:- Macleod-Brudenell, I,& Kay, J (2008, Second Ed) Advanced Early Years for Foundation Degrees & Level 4/5 Harlow: Heinemann Chapters 4, 5 and 9 Montessori Centre International (MCI) (undated a) Module 2 Child Development London: MCI Chapters 1 and 3 (pg 39 – 42) Montessori Centre International (MCI) (undated b) Module 4 Contemporary Issues London: MCIChapters 1, 3, 4 and 5 Montessori Centre Internat ional (MCI) (undated c) Module 5 Childcare and Health London: MCI Additional reading to consider for this assignment:- Montessori International (Issue 94, January – March) (Various articles in this issue of the magazine are relevant) Unicef (2008) Convention on the Rights of the Child, available from http://www. unicef. org/crc/ This assignment focuses on the importance of supporting the child’s well-being. Although, you will be given guidelines and additional reading material to assist you in the writing of this assignment, it is important for you to read as widely as you can.You will also need to consider the specific requirements within your own country. In these tutorial guidelines, the assignment question will be broken down into sections, giving you some pointers to consider when preparing your answer for submission. In order to enable you to focus on the different aspects of the questions, each has been given a weighting. These are the maximum marks that can be awarded for this part of the answer. The other 25% of the marks cover structure, expression and presentation (Take note of the marking table on the assessment sheet that you have received). WORKING ON THIS ASSIGNMENTBegin by:- †¢ Work through the recommended chapters listed above, making notes as you did for your Study Skills assignment. Please note that you are not limited to these chapters – You may also find it useful to do some independent research in your local library or on the internet. Be careful to limit your reading to academically sound sources – Wikipedia is not a safe site to use and should be avoided. (Remember to keep a record of the source document for later referencing and bibliography). †¢ Go through the extended guidelines below, and begin to gather information for your answer. Make note of any questions you have regarding this assignment and send them through to me. These questions and their answers will then form the second half of this f irst tutorial (the Q&A) which will be emailed to you so that you can take the information into consideration before finalising your essay for submission. Start to work on your answer:- 0 Study skills recap – †¢ Organise your information and thoughts into a logical, structured argument, addressing each of the important / main bullet points. Ensure that there is an overall flow to the information, and that each section links back to the question posed. Begin with an introduction that will state what you are going to cover in the main body of the essay. The introduction should be  ± 5-10% of the total length of the essay. Draw your argument to a conclusion at the end. †¢ Reference each time you paraphrase ideas you have read during your research for the essay, as well as the first time you include specific terminology in any one essay. In this essay you should ensure that you are quoting from academically sound sources. †¢ Find three or four relevant quotes that will support your argument.Use MCI protocol when referencing and quoting. CONTENT GUIDELINES FOR THIS ASSIGNMENT Identify and define the specific physical needs of a three year old child – including exercise and rest, diet, health and safety. (10) †¢ Briefly define what is meant by physical needs, including exercise and rest, diet, health and safety . †¢ Identify the specific physical needs of a three year old. Give a full explanation of how these physical needs should ideally be met by an early years setting/nursery which offers care from 8am to 6pm five days a week. (17. ) – Consider for example, how you could provide for gross and fine motor skills. Also think about safety issues (such as appropriate clothing for specific weather conditions), access to fresh air and ventilation in the classrooms, opportunities for rest, etc. – Give practical examples of what a setting would do to ensure the child’s well being as an essential pre-requisite to effective learning. Identify and define the psychological needs of a three year old child – focus on emotional and social needs. (10) †¢ Briefly define what is meant by psychological needs, focus on emotional and social needs.Your definition should briefly consider the needs for survival, participation and belonging. †¢ Identify the specific psychological needs of a three year old. Give a full explanation of how the psychological needs should ideally be met in an early years setting/nursery which offers care from 8am to 6pm five days a week. (17. 5) – Explain how the three year old’s emotional and social needs can be met. Here you should be looking at consistency, predictability and availability of care. – Explain how the children’s well-being and sense of belonging are promoted. Focus on settling in procedures and transitions, availability of a key person and liaison with parents. – Give practical examples of how you could make a three year old comfortable, settled, at ease and ready to actively participate in the daily life of the nursery. Having discussed the physical and psychological needs of a three year old relate these to relevant articles in the UNCRC (United Nations Convention on the Rights of the Child) which inform the statutory requirements for best practice in early years settings/nurseries in your country (20) –Briefly explore the general underlying principles (especially that of survival, protection and participation) which underpin the relevant articles of the UNCRC. (supplied with this tutorial) – Link these principles to the child’s needs. 0 Study skills recap – †¢ Your conclusion should summarise what you have said, without adding or introducing anything new. †¢ The word count includes references and quotes, but excludes bibliography †¢ Remember to use double line spacing and to number the pages of your document Finalising your answer:- †¢ R ead through your essay, checking your spelling, grammar and referencing format. Make sure your argument has a logical flow, and that you have answered each aspect of the question fully, in your own words. †¢ Fill in the cover sheet, including all necessary details. Check that your word count is within the accepted limit. †¢ Compile or finalise your bibliography using the correct format. (Follow the MCI protocol as outlined in your Student Handbook. ) 0 Study skills recap – Your bibliography must include full entries for all sources that you have referred to in your essay, as well as other books, articles, websites etc that you have read or consulted in preparation for this assignment.Bibliography:- Macleod-Brudenell, I, & Kay, J (2008, Second Ed) Advanced Early Years for Foundation Degrees & Level 4/5 Harlow: Heinemann Montessori Centre International (MCI) (undated a) Module 2 Child Development London: MCI Montessori Centre International (MCI) (undated b) Module 4 C ontemporary Issues London: MCI Montessori Centre International (MCI) (undated c) Module 5 Childcare and Health London: MCI